NAD+

In research environments, NAD+ is a central molecule involved in cellular energy metabolism, DNA repair, and the maintenance of redox balance. It supports sirtuin activation, which plays a key role in cellular stress-response pathways and the regulation of longevity-related mechanisms.

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Description

Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme found in all living cells and is fundamental to metabolic function. It participates in essential redox reactions, transferring electrons during key metabolic processes including glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation. In controlled laboratory settings, NAD+ is widely studied for its role in maintaining cellular homeostasis and regulating enzymatic activity in non-human research models.

NAD+ is also a required substrate for several important enzyme families—most notably sirtuins and poly (ADP-ribose) polymerases (PARPs)—which are involved in DNA repair, chromatin remodeling, and cellular stress-response signaling. Research suggests NAD+ contributes to mitochondrial function, energy production, and pathways associated with cellular resilience and longevity. Its involvement in oxidative stress regulation and inflammatory signaling makes it a key focus in studies examining metabolic and cellular health.

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Summary of Characteristics

Characteristic Details

Chemical Sequence Not applicable (non-peptide molecule)
CAS Number 53-84-9
Molecular Formula C₂₁H₂₇N₇O₁₄P₂
Molecular Weight 663.43 g/mol
Other Known Titles Nicotinamide adenine dinucleotide, β-NAD+, Coenzyme I

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Legal Disclaimer

This compound is sold strictly as a research-grade material and is not intended for human consumption or dietary use. Please review our Terms & Conditions prior to purchase.

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Safety Information

Keep out of reach of children.

This material has limited research available and improper handling may result in adverse effects.

This product is supplied solely as a raw research compound.

Only trained professionals with appropriate laboratory equipment should handle this material.

By purchasing or using this compound, you agree to indemnify us from any liability arising from misuse, improper handling, or consumption.

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Educational Notice

All information provided on this website is for research and educational purposes only. These materials are not pharmaceuticals, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any medical condition.